There are 1 repository under signaling-pathways topic.
gr-eventstream is a set of GNU Radio blocks for creating precisely timed events and either inserting them into, or extracting them from normal data-streams precisely. It allows for the definition of high speed time-synchronous c++ burst event handlers, as well as bridging to standard GNU Radio Async PDU messages with precise timing easily.
(DRExM³L) Drug REpurposing using eXplainable Machine Learning and Mechanistic Models of signal transduction
Finding paths of interest in networks
Converting KGML encoded KEGG pathways to the SIF file format
Converting SBGN encoded pathways to the SIF file format
Modeling signaling networks in cancer
Code for analysis of single cell signaling network kinetics from flow cytometry (CyTOF) datasets
A computational approach to predict the NF-kB inhibitors
Code repository for the publication. Contains MATLAB codes and sequence data used for evolutionary analysis.
Computations required for https://doi.org/10.1103/PhysRevE.97.020402 and additional work
Ligand-Receptor Interaction map based on scRNA-seq and pathway enrichment
Structure learning for protein signaling pathways
The functional analysis of genes provides relevant information to understand cellular function. Further, the mapping of genetic interactions sheds light on how genes act in the emergence of cellular complexity. Here, we present the most extensive genetic interaction and morphological profiling screen in a metazoan cell to date. We profiled 680 000 pairwise RNAi perturbations in more than 38 billion cells and analyzed 73 morphological features by high-throughput imaging.
Ph.D. dissertation submitted to the University of Michigan-Ann Arbor (accepted on May 23, 2022)
Code for modeling performed in Barney et al.
A kinetic model of dopamine- and calcium-dependent striatal synaptic plasticity (Nakano et al. 2010)
Rescue of plasticity by a computationally predicted protocol (Liu et al. 2013)
Computational modeling of gephyrin-dependent inhibitory transsynaptic signaling (Lupascu et al 2020)
An integrative dynamic model of brain energy metabolism (Coultier et al 2009)
Expression, biological and clinical relevance of the collagen pathway genes in prostate carcinoma