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R/MATLAB package to perform virtual knockout experiments on single-cell gene regulatory networks.
Package to gather gene information, annotations, and functions
ncRNA identification, annotation and functional prediction
The functional analysis of genes provides relevant information to understand cellular function. Further, the mapping of genetic interactions sheds light on how genes act in the emergence of cellular complexity. Here, we present the most extensive genetic interaction and morphological profiling screen in a metazoan cell to date. We profiled 680 000 pairwise RNAi perturbations in more than 38 billion cells and analyzed 73 morphological features by high-throughput imaging.