mechanism-of-action

There are 0 repository under mechanism-of-action topic.

• laylagerami / MAVEN

  Elucidate and visualise a compound's mechanism of action by combining structure-based target prediction with gene expression-based causal reasoning, plus pathway enrichment to put results into biological context. GUI-based (minimal coding experience required).

  bioinformaticschemoinformaticsmechanism-of-actionmoashiny-appsdrug-discoverycarnivaldorotheaprogenypidgin
  Language:R 12

• enveda / RPath

  Source code and data for "Causal reasoning over knowledge graphs leveraging drug-perturbed and disease-specific transcriptomic signatures for drug discovery"

  knowledge-graphcausal-networksdrug-discoverymechanism-of-actiontranscriptomicsnetwork-biology
  Language:Jupyter Notebook 11

• naim-panjwani / LocusFocus

  Application of the Simple Sum method for testing co-localization of GWAS with any other SNP-level data (e.g. eQTL data)

  gwasgwas-toolsgwas-summary-statisticseqtleqtl-mappinggtex-eqtl-associationmechanism-of-actioncis-regulationlocuszoomphewasfine-mapping
  Language:JavaScript 8

• cytodata / single-cell-classifier

  Software to classify biological phenotypes from single-cell image-based morphology profiles

  morphologymechanism-of-actionimage-classificationmachine-learningimage-based-profiling
  Language:HTML 7

• DylanSteinecke / BE298FinalProject

  Fall 2022 Bioengineering 298 Final Project: using protein networks to understand drug and disease mechanisms

  cardiovascular-diseasesgraph-algorithmsknowledge-graphsmechanism-of-actionmitochondria
  Language:Jupyter Notebook 0

• kimheeye / ISL_PKPD

  PK/PD framework to assess the pharmacological properties of Islatravir (ISL)

  pharmacokineticspharmacodynamicsislatravirmechanism-of-actionextrandeefficacy
  Language:Jupyter Notebook 0

• dinabandhu50 / PROJECT_MoA

  Multilabel classification using pytorch neuralnetwork, optimized hyperparameter using optuna.

  machine-learningmechanism-of-actionneural-networksoptunahyperparameter-optimizationmultilabel-classificationpython3jupyter-notebook
  Language:Jupyter Notebook

• SAGARSS24 / MTB_manuscript_data

  Physiological modeling into the metaverse of Mycobacterium tuberculosis beta CA inhibition mechanism

  drug-designmachine-learningmechanism-of-actionmechanistic-interpretabilitysystems-biologytuberculosis