p4rkerw / SALSA

Single Cell Allele-Specific Analysis - Containerized tool for genotyping, phasing, mapping bias correction, and generation of single cell allele-specific counts

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Welcome to 🌶️SALSA! Single Cell Allele Specific Analysis

Here you will find a workflow to analyze single cell allele-specific expression and chromatin accessibility obtained from 10X Genomics Single Cell Gene Expression and Single Cell ATAC datasets. To get started follow along with one of our tutorials.

If you use 🌶️SALSA please cite the following manuscript

Wilson PC, Muto Y, Wu H, Karihaloo A, Waikar SS, Humphreys BD.
Multimodal single cell sequencing implicates chromatin accessibility and genetic background in diabetic kidney disease progression
Nat Commun 13, 5253 (2022). 
https://doi.org/10.1038/s41467-022-32972-z
PMID: 36068241

Thanks!
Parker

Visit the Wilson lab website:
www.parkerwilsonlab.com

Visit the Humphreys lab website:
www.humphreyslab.com

Check out our interactive datasets with Kidney Interactive mulTiomics (KIT):
http://humphreyslab.com/SingleCell/

Find us on Twitter:
@parkercwilson @HumphreysLab

Find us on Docker Hub:
p4rkerw@dockerhub

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Single Cell Allele-Specific Analysis - Containerized tool for genotyping, phasing, mapping bias correction, and generation of single cell allele-specific counts

License:MIT License


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