Calculate sample size and power for association studies involving mitochondrial DNA haplogroups - Based on Samuels et al. AJHG, 2006. 78(4):713-720. DOI:10.1086/502682
Determine the minimum number of cases (Ncmin), required to detect: either a change from p0 (haplogroup frequency in controls) to p1 (haplogroup frequency in cases), or a given OR, with a predefined confidence interval, in a study with Nh haplogroups.
For a given study size, determine the minimum effect size that can be detected with the desired power and significance level, in a study with Nh haplogroups.