yyoshiaki / autoimmune10x_CD4T_Manuscript_2023

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Codes for Manuscript

Directories

CD4T_scRNAseq_atlas

Correspinding to Figures 1, 2.

NMFproj

NMFproj is available here https://github.com/yyoshiaki/NMFprojection.

meta_analysis

Reference mapping by symphony is available here https://github.com/yyoshiaki/screfmapping. The code needed for each project is included in the directory. Additionally, meta_analysis.v2.R is the analysis for the meta-analysis. Summary stats are availble here doi : 10.6084/m9.figshare.23983038.

sclinker

Pipeline are available in another repository https://github.com/yyoshiaki/sclinker-skg.

Data

Single-cell data can be explored interactively and downloaded in SingleCellPortal https://singlecell.broadinstitute.org/single_cell/study/SCP1963.

Publication

Single-cell transcriptome landscape of circulating CD4+ T cell populations in human autoimmune diseases Yoshiaki Yasumizu, Daiki Takeuchi, Reo Morimoto, Yusuke Takeshima, Tatsusada Okuno, Makoto Kinoshita, Takayoshi Morita, Yasuhiro Kato, Min Wang, Daisuke Motooka, Daisuke Okuzaki, Yamami Nakamura, Norihisa Mikami, Masaya Arai, Xuan Zhang, Atsushi Kumanogoh, Hideki Mochizuki, Naganari Ohkura, Shimon Sakaguchi bioRxiv 2023.05.09.540089; doi: https://doi.org/10.1101/2023.05.09.540089

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