Shiny app for "Single-cell multi-omics profiling links dynamic DNA methylation to cell fate decisions during mouse early organogenesis"
This repository contains the code for the R shiny app for the Dnmt1-/-, Dnmt3a-/- and Dnmt3b-/- KO analysis of our study Single-cell multi-omics profiling links dynamic DNA methylation to cell fate decisions during early mouse organogenesis. It covers most of Figures 1-2 as well as Supplementary Figures 1-4. The source code for the second part of the paper, where we explore the Tet-TKO embryos, is available in this repository
Link to the app: https://www.bioinformatics.babraham.ac.uk/shiny/shiny_dnmt/