Application to WGS
mflevine opened this issue · comments
Hi, do you think that this method could be applied to high coverage >80x whole genome sequencing? Also will this only identify fusions from simple rearrangements or also from multi-breakpoint events?
Hi @mflevine,
Thank you for your interest in FuSeq_WES.
I think whole genome sequencing data with high coverage >80x would work. In our DNA-seq of a gene panel, FuSeq_WES secures the sensitivity for > 75x coverage.
In principle, the tool will report all fusion events, so including multi-breakpoint events.
Best,
Nghia