Application to WGS

[Max Levine]

Hi, do you think that this method could be applied to high coverage >80x whole genome sequencing? Also will this only identify fusions from simple rearrangements or also from multi-breakpoint events?

[Trung Nghia Vu]

Hi @mflevine,

Thank you for your interest in FuSeq_WES.

I think whole genome sequencing data with high coverage >80x would work. In our DNA-seq of a gene panel, FuSeq_WES secures the sensitivity for > 75x coverage.

In principle, the tool will report all fusion events, so including multi-breakpoint events.

Best,
Nghia