crisprVerse / crisprDesign

Comprehensive design of CRISPR gRNAs for nucleases and base editors

crisprVerse/crisprDesign Issues

Validating Existing gRNA Libraries - Error in Off-Target Characterization (addSpacerAlignment)
Closed a year ago7
Support guide efficiency prediction for DjCas13d [feature request]
Updated 5 months ago1
AddOnTargetScores unable to run due to error with creating conda environment
Updated 5 months ago2
Error building gene annotation object with GFF for CHM13v2.0
Closed 6 months ago3
Design spacer for CRISPR-Csm transcript targeting systems [feature request]
Updated 6 months ago2
GuideSet2DataFrames: improvements
Updated 6 months ago
MIT/CFD scores when spacers are duplicated
Updated 6 months ago
error when constructing a tssObject using yeast gff file
Closed a year ago2
DNA and RNA bulge off target DSB
Closed a year ago1
CrisprVerse problem: export a guideSet in a file
Closed a year ago2
Increase barcode length for Levenshtein distance
Closed a year ago
`addSpacerAlignments` fails to find off-targets with bowtie and custom genomes
Closed a year ago5
`max_mm` vs `n_mismatches`
Closed a year ago2
Alignments error while using `PairedGuideSet` object as input
Updated a year ago2
`addSpacerAlignments` maximum `n_mismatches` query
Closed a year ago1
addSpacerAlignments Error in .new_IRanges_from_start_width(start, width) : 'start' or 'width' cannot contain NAs
Closed a year ago6
Change default to FALSE for standard_chr_only
Closed a year ago1
len arguments in spacers accessor function
Updated a year ago
guideSetExampleFullAnnotation lacking exon_id in geneAnnotation.
Closed a year ago1
what's the meaning of "alignments" in GuideSet object ?
Closed a year ago2
Web UI crisprVerse designer
Closed a year ago1
`addSpacerAlignmentsIterative` – Error in `curl::curl_fetch_memory`
Closed a year ago3
I don't konw why but the off-targets found by addSpacerAlignments was abosolutlely wrong?
Closed 2 years ago1
"downstreamATG" colname misspelled
Closed 2 years ago
The style specified by 'NCBI' does not have a compatible entry for the species Danio rerio
Closed 2 years ago1
onTargets for guideSet object always get nothing
Closed 2 years ago