cepdnaclk / e18-4yp-Multi-Kingdom-Binning-of-Long-Read-Metagenomes

A tool for refining long-reads binning using kingdom level information

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Long-reads Binning For Microbial Metagenomics Considering Multi-kingdoms


Description

Metagenomics has shown a rising interest towards using long reads from third-generation sequencing (TGS) technologies to overcome the limitations of short reads in resolving structural and functional aspects of genomes. As these sequences are long enough to hold species-specific signals, they can be grouped into bins of different taxonomic groups.

Previous studies have already shown that binning long reads based on nucleotide composition and abundance information significantly improves the quality of downstream metagenome assemblies. This project aims to develop a method to bin long reads from multiple metagenomic samples while being aware of the underlying microbial kingdoms.

Team members

  • Aththanayaka A.M.S. (E/18/030)
  • Ranasinghe R.A.N.S. (E/18/282)
  • Ranasinghe R.D.J.M. (E/18/283)

Supervisors

  • Dr. Damayanthi Herath
  • Dr. Vijni Mallawaarachchi

About

A tool for refining long-reads binning using kingdom level information


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