d4-nim
This is a nim wrapper for Hao Hou's d4 which can be thought of as a way to store integer data in a compressed array. A common use-case will be depth storage and querying. His library also has a command-line depth extractor that is faster than mosdepth. The extracted (compressed) file can quickly queried for summary info such as mean depth of a region.
Usage in nim looks like:
var d4f:D4
doAssert d4f.open("hg002.d4")
echo d4f.chromosomes # ordered table
echo d4f.chromosomes["1"]
for iv in d4f.query("1", 249_200_100):
echo iv # (tuple of start:uint32, end:uint32, value:int32)
var start = 249_200_100'u32
var stop = 249_240_621'u32
# each entry in vals contains the depth for pos-start
var vals:seq[int32] = d4f.values("1", start, stop)