bips-hb / srsim

An R package for simulating spontaneous reports

Simulating Spontaneous Reporting Systems (SRSim)

Spontaneous reporting systems are used in the field of pharmacovigilance to detect (previously unknown) associations between drugs and adverse events (AEs). This R package allows for simulating large spontaneous reporting data sets. See https://srs.bips.eu/ for an example on how this simulator could be used.

Installation

To install, simply type in R

devtools::install_github("bips-hb/srsim")

Usage

See for usage the function descriptions, especially

?SRSim::simulateSRS

References

Please cite

Adverse Drug Reaction or Innocent Bystander? A Systematic Comparison of Statistical Discovery Methods for Spontaneous Reporting Systems
L.J. Dijkstra, M. Garling, R. Foraita & I. Pigeot
Pharmacoepidemiology and Drug Safety (2020)
DOI:10.1002/PDS.4970

Acknowledgements

We gratefully acknowledge the financial support from the innovation fund (“Innovationsfonds”) of the Federal Joint Committee in Germany (grant number: 01VSF16020).

Contact

Louis Dijkstra
Leibniz Institute for Prevention Research & Epidemiology
E-mail: dijkstra (at) leibniz-bips.de