scRNA melanoma paper
Scripts related to the current version of our manuscript entitled "Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma" published in Nature Cell Biology, previously available on bioRxiv.
All scRNA-seq data, including SCENIC analyses, are available online as .loom files on our single-cell analysis platform SCope.
The scRNA-seq gene expression data is also available on the UCSC Cell Browser.
A track hub for the UCSC Genome Browser with bigwig and BED files of our ATAC-seq data (in hg19 and hg38) is available here.
The single-cell and bulk RNA-seq and ATAC-seq data have also been deposited in GEO under the accession number GSE134432.
Raw images, tracking information and videos for the single-cell migration experiments, and raw data, images and videos for the bulk migration experiments, are made available on the Open Science Framework of the Center for Open Science.
All gene regulatory networks (GRN) in the manuscript are made available on the Network Data Exchange NDEx: the global melanoma GRN, the intermediate GRN and a highly refined SOX10 regulon.