Run AUCell_buildRankings on HVG?
aelhossiny opened this issue · comments
Hi, thank you for such a wonderful tool,
I've an integrated dataset of ~121k cells with ~50k features, running AUCell_buildRankings()
on this dataset keeps giving me that error
Error in asMethod(object) :
Cholmod error 'problem too large' at file ../Core/cholmod_dense.c, line 102
I understand that this is a memory issue, can I run it on the top 2000 HVG as it's routinely done in other analyses? Or is it better to run it on individual samples separatly on whole genes?
Sorry, for questions on how to use the package, see:
#26