Modeling of published clinical Itraconazole-Tacrolimus-DDI studies for model evaluation
Within this repository, we distribute a PK-Sim snapshot containing simulations of all published clinical studies used to evaluate the predictive performance of the tacrolimus model regarding itraconazole-tacrolimus-DDIs, including the respective observed data digitized from literature reports. The applied itraconazole model has been published previously [1]. For further details and documentation please refer to [2].
PK-Sim Version 10.
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The model is distributed under the GPLv2 Lincense.