CINPLA / EDPRmodel

An electrodiffusive, ion conserving Pinsky-Rinzel model with homeostatic mechanisms

EDPRmodel

EDPRmodel is an implementation of the KNP continuity equations for a one-dimensional system containing two plus two compartments. The model is presented in Sætra et al., PLoS Computational Biology, 16(4), e1007661 (2020): An electrodiffusive, ion conserving Pinsky-Rinzel model with homeostatic mechanisms.

Installation

Clone or download the repo, navigate to the top directory of the repo and enter the following command in the terminal:

python setup.py install

The code was developed for Python 3.6.

Run simulations

The simulations folder includes example code showing how to run simulations. To reproduce the results presented in Sætra et al. 2020, see https://github.com/CINPLA/EDPRmodel_analysis.