Data and Computational Biology Group UNIMIB (was BI*oinformatics MI*lan B*icocca)'s repositories
LACE
LACE 2.0 is a new release of the LACE R Bioconductor package, which provides an interactive user interface to perform clonal evolution analyses for single-cell sequencing data, including longitudinal experiments. The tool also allows to annotate and retrieve the relevant variants based on user-defined criteria.
J-Space.jl
J-SPACE is a Julia package to simulate the spatial growth and the genomic evolution of a cell population and the experiment of sequencing the genome of the sampled cells.
SARS-CoV-2-IHMV
Utilities repository to replicate the analyses presented in https://www.cell.com/iscience/fulltext/S2589-0042(21)00084-5
PMCE
GitHub repository of the PMCE Framework. F. Angaroni, K. Chen, C. Damiani, G. Caravagna, A. Graudenzi, D. Ramazotti, PMCE: efficient inference of expressive models of cancer evolution with high prognostic power, Bioinformatics, 2021; btab717, https://doi.org/10.1093/bioinformatics/btab717
VERSO-UTILITIES
Utilities repository for VERSO (Viral Evolution ReconStructiOn); main tool repository: https://github.com/BIMIB-DISCo/VERSO
Accelerated-globalSA-of-constraint-based-models
Accelerated global sensitivity analysis of genome-wide constraint-based metabolic models
JHistint.jl
Julia interface for implementing REST APIs available on the CDSA (Cancer Slide Digital Archive) portal for managing histological images available from TCGA. The library includes functions for managing image processing algorithms for cell segmentation, constructing the adjacency matrix, tessellation process and interfacing with J-Space.jl.
LACE-UTILITIES
Utilities repository for LACE (Longitudinal Analysis of Cancer Evolution); main tool repository: https://github.com/BIMIB-DISCo/LACE
SARS-CoV-2-early-detection
In this repository we provide the code to replicate the early detection analysis of SARS-CoV-2 variants from deep sequencing samples. Please feel free to contact us if you have any question on the pipeline at: daniele.ramazzotti1@gmail.com
SOPHYSM.jl
SOPHYSM - SOlid tumors PHYlogenetic Spatial Modeller - Julia GUI for Histological Analysis and Cancer Simulation