Data and Computational Biology Group UNIMIB (was BI*oinformatics MI*lan B*icocca) (BIMIB-DISCo)

Data and Computational Biology Group UNIMIB (was BI*oinformatics MI*lan B*icocca)

BIMIB-DISCo

Geek Repo

The github organization of the DCB group of the DISCo, Università degli Studi di Milano Bicocca

Home Page:http://dcb.disco.unimib.it

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Data and Computational Biology Group UNIMIB (was BI*oinformatics MI*lan B*icocca)'s repositories

TRONCO

Repository of the TRanslational ONCOlogy library, which includes various algorithms (such as CAPRESE and CAPRI) and the Pipeline for Cancer Inference (PICNIC).

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LACE

LACE 2.0 is a new release of the LACE R Bioconductor package, which provides an interactive user interface to perform clonal evolution analyses for single-cell sequencing data, including longitudinal experiments. The tool also allows to annotate and retrieve the relevant variants based on user-defined criteria.

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VERSO

Viral Evolution ReconStructiOn (VERSO). The manuscript of the method is available at: https://www.cell.com/patterns/fulltext/S2666-3899(21)00022-2

J-Space.jl

J-SPACE is a Julia package to simulate the spatial growth and the genomic evolution of a cell population and the experiment of sequencing the genome of the sampled cells.

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SARS-CoV-2-IHMV

Utilities repository to replicate the analyses presented in https://www.cell.com/iscience/fulltext/S2589-0042(21)00084-5

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CT4TD

Control Theory for Therapy Design

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LACEView

A tool to visualize LACE output.

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PMCE

GitHub repository of the PMCE Framework. F. Angaroni, K. Chen, C. Damiani, G. Caravagna, A. Graudenzi, D. Ramazotti, PMCE: efficient inference of expressive models of cancer evolution with high prognostic power, Bioinformatics, 2021; btab717, https://doi.org/10.1093/bioinformatics/btab717

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TRaIT

Source code and input data to reproduce the case studies presented in the TRaIT framework: https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-019-2795-4

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VERSO-UTILITIES

Utilities repository for VERSO (Viral Evolution ReconStructiOn); main tool repository: https://github.com/BIMIB-DISCo/VERSO

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VirMutSig

The VirMutSig protocol is available at: Maspero, D. et al. "VirMutSig: Discovery and assignment of viral mutational signatures from sequencing data", STAR Protocols 2.4 (2021): 100911. https://doi.org/10.1016/j.xpro.2021.100911

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Accelerated-globalSA-of-constraint-based-models

Accelerated global sensitivity analysis of genome-wide constraint-based metabolic models

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OG-SPACE

Public repository of OG-SPACE

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ANNAPD

Artificial Neural Networks Activation Pattern Diagram

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DCB-Theme

Beamer theme for DCBLab LaTeX slides

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JHistint.jl

Julia interface for implementing REST APIs available on the CDSA (Cancer Slide Digital Archive) portal for managing histological images available from TCGA. The library includes functions for managing image processing algorithms for cell segmentation, constructing the adjacency matrix, tessellation process and interfacing with J-Space.jl.

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LACE-UTILITIES

Utilities repository for LACE (Longitudinal Analysis of Cancer Evolution); main tool repository: https://github.com/BIMIB-DISCo/LACE

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ProPhET

Probabilistic PHylogeny Extraction Tool

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SARS-CoV-2-early-detection

In this repository we provide the code to replicate the early detection analysis of SARS-CoV-2 variants from deep sequencing samples. Please feel free to contact us if you have any question on the pipeline at: daniele.ramazzotti1@gmail.com

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SOPHYSM.jl

SOPHYSM - SOlid tumors PHYlogenetic Spatial Modeller - Julia GUI for Histological Analysis and Cancer Simulation

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