Tried to work with Node.js Alpine linux APK build with andyshinn's docker alpine abuild tool.
Seems having problem (attr_set not supported) on Mac OSX xhyve, so have this repo created for workaround, if you prefer to stick on official APKBUILD file.
UPDATE: For people would like not use any VM at all, simple switch off paxmark with paxctl, and replace all:
paxmark -c /path/to/target
to
paxctl -cm /path/to/target
Have tested this work under Mac OS X El Capitan & Docker 1.12.1.