httkgui was a proof of concept modification of a popular CRAN toxicokinetics package httk (v1.4); httkgui modifies some of the TK models, allows rudimentary Monte Carlo simulations of said models and provides GUI ("TKPlate") to run them and review the results
The original 'httk' (v1.8 as of Jan 2019) package is by John Wambaugh. The code modifications to 'httk' have been developed by Witold Wiecek with concept by Nadia Quignot and Billy Amzal at Analytica Laser (now Certara) as a part of an European Food Safety Authority project “Integrating toxicokinetics in chemical risk assessment: application to human, animal and environmental risk assessment” (OC/EFSA/SCER/2014/06)
Core functions are same as in httk. Changes to models are not documented within code but version controlled.
devtools::install_github("wwiecek/httkgui")
library(httkgui)
pbtkUI() #Proof-of-concept GUI