ftd2xx is a simple python wrapper around the D2XX DLL from FTDI using ctypes. The API based on Pablo Bleyer Kocik's d2xx extension.
Version 1.1.0 is compatible with Python 3. Please ensure you have FTDI drivers installed or available where the linker looks for shared libraries (e.g., PATH on windows, LD_LIBRARY_PATH or standard library directories on Linux)
I don't have time to maintain this project, so I am looking for a maintainer.
There is another library by Ben Bass called pylibftdi that may fit your needs better.
Also, Jeremy Bentham wrote a blog about using this library.