wisekh6 / gm-cells-chiadrop

Scripts to reproduce results presented in "Single-molecule mapping reveals the dynamics of chromatin folding in the human genome"

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Human chromatin folding dynamics

This repository contains scripts to reproduce results presented in "Single-molecule mapping reveals the dynamics of chromatin folding in the human genome" by Kim, Wang, Clow et al.

Processed data files can be downloaded from: https://thejacksonlaboratory.box.com/s/x2pu8bn55rfv2ztegqzp1n9ez42mpobe

  • "ipynb" folder has ipython notebook scripts to process files and generate plots.
  • "readmefiles" folder contains text files that describe input and output for files in the "scripts" folder.
  • "scripts" folder includes codes to sort ChIA-Drop complexes in 1-sided or 2-sided manner, compute slope, and to aggregate 2d contact maps over many regions.

For questions or bug reports, contact Minji (minji.kim@jax.org) or visit the "Issues" page.

Code contributors: Minji Kim, I (Eli) Chien, Xiaotao Wang, Jianhao Peng

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Scripts to reproduce results presented in "Single-molecule mapping reveals the dynamics of chromatin folding in the human genome"

License:MIT License


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