vallurumk / APA-Scan

Detection and visualization of annotated and potential Alternative Polyadenylation events

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APA-Scan

APA-Scan detects the potential Alternative Polyadenylation (APA) events in the downstream 3'-UTR of a gene among two different biological conditions.

Installation

APA-Scan is a python tool which can be downloaded directly from github. Python (version 3.0 or higher) is required to be installed on users machine to run APA-Scan. It can work on Windows, Linux and Mac platform.

Users need to run the specific file APA-scan.py to demonstrate the APA events.

$python3 APA-scan.py

To generate plots for any selected 3'-UTR region, users need to run makePlots.py and provide input in a specific pattern: chromName:geneName:start-end

$python3 Make-plots.py

User manual

User manual for APA-Scan is available on github https://github.com/compbiolabucf/APA-Scan/blob/master/APA-Scan%20User%20Manual.pdf

Citation

Please use the following information to cite...(will add later)

Contact the Author

Naima Ahmed Fahmi: fnaima@knights.ucf.edu Wei Zhang: wzhang.cs@ucf.edu Jeongsik Yong: jyong@umn.edu

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Detection and visualization of annotated and potential Alternative Polyadenylation events


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