cpg-signature-design

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RRafiee / MIMIC
Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures - We describe the development and validation of minimal methylation classifier (MIMIC), combining CpG signature design from genome-wide datasets, multiplex-PCR and detection by single-base extension and MALDI-TOF mass spectrometry, in a novel method to assess multi-locus DNA methylation profiles within routine clinically-applicable assays.
methylation dna-methylation classification minimal classifier-model svm svm-classifier training shiny shiny-server user-interface ui server 17-cpgs mimic subgroups medulloblastoma diagnostics maldi-tof-mass-spectrometry cpg-signature-design
Language:R

RRafiee / MIMIC