Based on this tutorial
To run locally, you can use any development HTTP server and point it to this directory. For example:
python -m http.server 9000
Then, open http://localhost:9000/launch.html in your browser.
Currently, it points to the SMART IT DSTU2 Sandbox. To point to another SMART on FHIR server, modify the iss parameter in launch.html. Note that you may also need to modify the clientId and clientSecret parameters as well.