Stephens lab (stephenslab)

Stephens lab

stephenslab

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Research in statistical and computational methods for genetics at the University of Chicago.

Home Page:http://stephenslab.uchicago.edu

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Stephens lab's repositories

ash

Code and analyses from "FDR: A New Deal" paper

mashr-paper

Multivariate adaptive shrinkage methods used for analysis GTEx data in Urbut et al (2017).

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count-clustering

Code and data reproducing results from our PLOS Genetics paper "Visualizing the structure of RNA-seq expression data using grade of membership models"

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EbayesThresh

R package for Empirical Bayes thresholding and related methods.

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fast-ash

Repo for work related to making adaptive shrinkage algorithms faster

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multiseq

Development of software and methods for analysis of sequence data from multiple samples

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cormotif

Correlation motif model.

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dscr-smash

Source code implementing Gaussian denoising simulations for Xing & Stephens (2016).

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EbayesThresh_from_kan

R package for Empirical Bayes thresholding and related methods

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EBNM-moderated-t

Code and analyses for the "EBNM" project (Empirical Bayes estimation of normal means, accounting for uncertainty in estimated standard errors).

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gtex-zcorr

investigate correlations in gtex z scores

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mash-application-immune

Applying mash methods to data from Kim-Hellmuth et al (2017).

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pps-cluster

Documentation for the PPS cluster (pps-gateway.uchicago.edu), including the upgrade to Red Hat 7.3 (the "Simple Revitalization Plan")

stephenslab.github.io

Github Pages for the Stephens lab.

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toolbox

Core set of computational tools & practices used in the Stephens lab to improve research productivity.

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ashlar

Workflow template

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confounding-polygenic

For discussing work related to confounding vs polygenicity

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dashr

R package for Dirichlet adaptive shrinkage and smoothing

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DDD

slides for DDD site visit

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dsc-blm

DSC benchmark for Bayesian linear models.

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dsc-normalmeans

repo for dynamic statistical comparison of normal means methods

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dsc-regression

Application of DSC2 framework to a range of regression models.

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ebayesthresh2

Work on possible extensions to ebayesthresh—see stephenslab/ebayesthresh.

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fast-ash.orig

repo set up to investigate ideas to make ash faster

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miximash

MIXtures of Independent components in Multivariate Adaptive SHrinkage ("miximash").

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shinydsc

R package and shiny application for exploring and visualizing dsc2 results

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simple_site

Minimal tutorial on making a simple website with GitHub Pages

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Trans-eQTL

Trans-eQTL joint with Barbara Engelhardt

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