Running pairwise analysis downstream of multi-way comparison

[Steve Lianoglou]

Greetings,

I like the idea of leveraging the multi-way analysis for larger experiments, but I'd also like to run specific pairwise analyses between some the groups from the multi-way analysis.

The appeal of being able to do this to me is so that we can reuse the same group_id and intron definitions between the two analyses, making it a bit more straightforward to identify the same splicing event between the two comparisons.

Is there someway to do that? It seems to me that after running the multi-way analysis, it looks like all of the necessary data (like counts supporting splicing events) has already been calculated and stored in the intron_data.txt and group_data.txt files, is that right?

I'd essentially like to use those as input to then create another set of diff_*.txt files that provide the statistics for a specific pairwise analysis between two of the groups that already made their appearance in the multi-way test.

[Ed Lui]

Thank you for your great suggestion. We'll evaluate the idea and investigate potential implementation paths. I appreciate your continued feedback and support!