Flask-AdminLTE packages AdminLTE into an extension that mostly consists of a blueprint named 'adminlte'. It can also create links to serve AdminLTE from a CDN and works with no boilerplate code in your application.
If you're not already using virtualenv then I strongly recommend you do, it's just going to make your life a whole lot easier. The Flask Mega Tutorial has instructions on setting up virtualenv.
Optional but recommended step to use a virtualenv:
virtualenv myapp pip install -r requirements.txt
There is a sample application in sample_application/ which you can adapt to your needs. After installing the requirements run it from the project directory:
python run_sample_application.py
Here is an example:
from flask_adminlte import AdminLTE [...] AdminLTE(app)
This makes some new templates available, containing blank pages that include all bootstrap resources, and have predefined blocks where you can put your content.