npm install nodejs-box
First, you need to go through the OAuth2 process with Box.com, so that you can receive an access token. I recommend the box-passport module to help with this.
var Box = require('nodejs-box');
var box = new Box({
access_token: 'YOUR_ACCESS_TOKEN_GOES_HERE',
refreh_token: 'YOUR_REFRESH_TOKEN_GOES_HERE'
});