secrierlab / IDH_mutant_glioma_subtypes

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IDH mutant glioma subtypes

Authors: Guidantonio Malagoli Tagliazucchi, Maria Secrier


This repository contains code developed for the analysis presented in Shroff et al.


Folder structure:

methylation_scripts

Scripts developed for the analysis of methylation data from mouse and in TCGA and Turkan et al.

DMR_analysis

Analysis of TF targets in differentially methylated regions (DMR).

gene_expression_scripts

Clustering of TCGA samples based on the murine gene expression signature.

lineage_analysis

Analysis of lineage signature enrichment in bulk RNA-seq data from the mouse model and human tumours from TCGA.

TME_deconvolution

Deconvolution of the tumour microenvironment cell populations in bulk murine and TCGA data.

T_cell_exclusion

Analysis of T cell exclusion in bulk sequenced TCGA subgroups.


Copyright

This code is free and is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY. See the GNU General Public License for more details.

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License:GNU General Public License v3.0


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