pNUK73 provides a simple Metropolis-Hastings MCMC method to estimate growth kinetic parameters (mu, Ks, rho) that fit growth curves measured as bacterial optical densities. It also implements a data cloning algorithm [Lele et al. (2007), Lele et al. (2010)] to assess the identifiability of the parameters.
Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids. A. San Millan, R. Peña-Miller, M. Toll-Riera, Z.V. Halbert, A.R. McLean, B.S. Cooper and R.C. MacLean. Nature Communications (in review).