neyhartj / breeding-notes

Simple repository of links to tools for plant breeding and genetics

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breeding-notes

Simple repository of links to tools for plant breeding and genetics, with some annotation. This is for information purposes only.

Mixed-models

A section on mixed-models. See my other repository on examples of mixed-model applications for plant breeding experiments.

R packages

  • CRAN task view for mixed-models
  • lme4
    • Can be forced to fit compound symmetry, unstructured, and diagonal covariance structures
  • glmmTMB
    • Allows for some cool covariance structures, including Toeplitz, AR1, spatial exponential; see here
  • blme
    • Extends lme4 and allows for prior distributions; it also allows for the residual variance to be fixed (useful for two-stage analysis)
  • rrBLUP
    • Very nice for a single random effect; the go-to for genomewide selection
  • sommer
    • Great for mixed models with multiple random effects and with kinship
  • lme4GS
    • lme4 language with flexibility for kinship; in theory the more complex covariance structures of lme4 (us, cs, diag) could be deployed
  • asreml
    • The gold standard for quickly fitting models with complex covariance sturctures, but you need a license
  • mmrm
    • Mixed-models for repeated measures; allows for time-dependent covariance structures like AR1, ante, toep, and exp

Tutorials

QTL mapping / GWAS

R packages

  • The Biometris group has several useful R packages:
    • statgenGWAS
      • single-trait GWAS
    • statgenQTLxT
      • multi-trait, multi-environment GWAS
    • statgenIBD
      • Calculate identity-by-decent probabilities in two-, three-, and four-way crosses

Tutorials

GxE

R packages

  • statgenGxE
    • Mega-environment analysis, stability, FW-regression, AMMI and GGE, etc. all the fun stuff
  • statgenSTA
    • Mixed-model analysis of field trials with or without spatial trends

Tutorials

Phenomics

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Simple repository of links to tools for plant breeding and genetics