Explain methods diagrammatically
bschilder opened this issue · comments
Our analyses and the number of steps have grown, so would be good to explain this in a more understandable way (for ourselves and for readers).
I will:
- write an outline describing all the methods in our rare diseases paper, including the new methods ive been developing lately for identifying celltype-driven differential outcomes, and disease-celltype enrichment analyses, and making connections between disease-phenotypes-celltype-genes
- visualize this as a diagram, which may serve as a supplementary figure in the manuscript
Outline version
Diagrammatic version
Here's a more abstract attempt to explain the approach:
@NathanSkene you can find the step-by-step approach I took explained here, specifically the Link cell types to symptoms section:
#24 (comment)
I will also provide a specific example from our results.
I think i've managed to do this effectively in my ISMB presentation. As @NathanSkene and I have discussed, I will use elements of how I communicated my work in this presentation to update the Rare Diseases manuscript: