mingwhy / bioinfo_homemade_tools

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bioinfo_dataBase

Name Date
KEGG database usage 2021-07-07
fly gene age inference by phylostratigraphy 2021-07-07
FlyXCDB-A Resource for Drosophila Cell Surface and Secreted Proteins and Their Extracellular Domains 2021-07-07
Fly gene regulatory network of TF-target database 2021-07-07
FlyBase gene group usage 2021-07-07
FlyBase gene GO annotation 2021-07-07
Classify fly genes into functional categories 2021-07-07
Essential gene database 2021-07-07
Fly protein complex database 2021-07-07
Metazoan protein complex database 2021-07-07
Panther GO slim terms 2021-07-07
Fly genes divergence measured by dN, dS 2021-07-07
PPI database (string, biogrid) 2021-07-07
Flycircuit 2021-08-26
GO terms map to genes 2021-09-04
DroID_TF-gene interaction 2021-09-07
fly X.chr, distance between dosage.compensation.complex and HAS 2021-11-02
fly metabolomics 2021-11-12
Gene Origin inference by phylostratigraphy 2022-11-22

additional bioinfo_database

Name Description Note
Orthodb the hierarchical catalogue of orthologs, example R parsing script
homologene An r package that works as a wrapper to NCBI HomoloGene Updating the good old Homologene database
InParanoid ortholog groups with inparalogs in-paralogs,out-paralogs,orthologs
EggNOG a hierarchical, functionally and phylogenetically annotated orthology resource
GenTree The time tree of genes along the evolution history human and fly age data available
GenOrigin GenOrigin: A comprehensive protein-coding gene origination database on the evolutionary timescale of life Original paper
GeneAge This section of GenAge features genes associated with ageing and/or longevity in model organisms.

Useful documents:

Converting single-cell data structures between Bioconductor and Python

Scripts showcases:

KnowledgeBase outline:

theory

  • quantitative genetics
  • population genetics
  • life history evolution Aging Sex difference Developmental biology

empirical

  • lab experiment
  • natural population
  • cross-species divergence or convergence
  • temporal, spatial, group (condition: time points, various tissues, sex)

method

  • G matrix, additive genetic var, heritibility
  • Ne, selection coefficient, site frequency spectrum, coalescent

math and stats

  • matrix facterization
  • random matrix
  • diffusion process (drift, cell lineage)
  • dynamic system (discrete, matrix, cell kinetics)
  • multi-level model (linear mixed model)
  • entropy (aging)
  • Structural equation modelling (SEM)

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