Summarize methylation statistics from bisulfite DNA-seq libraries
mdshw5 opened this issue · comments
Matt Shirley commented
Some recent BS-seq programs store methylation information in a SAM tag. One example is Bismark. A flag for --methylation
would activate routines for summarizing:
- Cycle-specific CpG cytosine methylation
- Cycle-specific cytosine conversion
- Methyl-C content percent per read
Matt Shirley commented
Since there are only a few data formats for representing methylation data from bisulfite sequencing, flags for --bismark
, --bsmap
etc.. might be useful.