An R package which implements a method for estimation of a causal effect in a Mendelian randomization setting as described in
Grant, A.J. and Burgess, S. (2019). An efficient and robust approach to Mendelian randomization with measured pleiotropic effects in a high-dimensional setting. arXiv:1911.00347
library(devtools)
install_github("aj-grant/mvcovreg")
docker build -t mrcovreg:latest .
docker run -it mrcovreg R
The file Urate_CHD_script.R in the example folder replicates the applied example in the paper.
The simulations folder contains R scripts to replicate the simulations presented in the paper.