legaultmarc / grstools

A bioinformatics framework for the construction and evaluation of genetic risk scores

https://legaultmarc.github.io/grstools/

legaultmarc/grstools Issues

Selection when variants are not covered in the reference panel
Closed 6 years ago1
Allow selection based on FDR q-value
Updated 6 years ago2
Automatic tag selection
Closed 6 years ago1
Expected / Observed beta plot
Closed 7 years ago
Add risk allele frequency column to grs format
Updated 7 years ago
Positive weighting
Closed 7 years ago
Implement 2SLS for the MR module instead of the ratio method
Updated 7 years ago
supplementary info in grs file
Updated 7 years ago
Multiple mappings in the mapper
Closed 7 years ago1
Empirical power/sensitivity for MR
Updated 7 years ago
Sample trajectories
Updated 7 years ago
Add "indentity" mapper
Closed 7 years ago1
Add a n, beta, p-value wrt. centile threshold plot
Closed 7 years ago