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Science Digest Topics

58 - Jan 28 2022

  • Compound derived from walnuts and pomegranates may boost mitochondrial and muscle health.
  • Not getting enough sleep increases common cold risk.
  • Drinking tea may reduce the risk of cardiovascular disease and premature death.
  • Fiber-rich diets may reduce the risk of all causes of premature death.
  • Retinas predict biological age and risk of premature death.
  • Specialized cells in the gut differentiate between sugar and artificial sweeteners.
  • Memory reactivation during sleep enhances ability to recall faces and names.
  • Having "mono" increases risk for multiple sclerosis later in life.
  • Exercise reverses aspects of brain aging.
  • Goji berries increase carotenoid density in the eye, but supplements don't.

57 - Jan 14 2022

  • Exercise preserves connections in the brain, providing protection against Alzheimer's disease.
  • Compounds produced during ketosis may slow prostate cancer growth.
  • Defensive compounds in plants may protect against Alzheimer's disease.
  • Drinking sugar-sweetened beverages increases risk of death from any cause among women with breast cancer.
  • Bedtime light exposure supresses melatonin levels in pre-school children by as much as 98 percent.
  • Doubling choline supplementation during pregnancy improved children's attention at seven years of age.
  • Shorter sleep duration promotes the intake of added sugars and carbohydrates.
  • Meditation helps the brain detect and respond to mistakes.
  • SARS-CoV-2 infection may cause autoimmune disease, especially in men.
  • Breastfeeding reduces maternal risk of cardiovascular disease later in life.

15 - May 29 2020

  • Recovered COVID-19 patients carry T-cells that might promote long-term immunity.
  • Omega-3 fatty acids decrease oxidative stress and affect biomarkers of aging.
  • Exercise improves blood flow to the brain and cognitive function in older adults.
  • Magnesium intake associated with reduced risk of coronary artery calcification.
  • Low magnesium levels associated with impaired vitamin D metabolism.
  • Aerobic exercise counters the harmful effects of consuming sugar-sweetened beverages on the endothelial function.
  • Aerobic exercise induces changes in blood flow in brain regions involved in memory.
  • Regular physical exercise reduces the incidence of dementia in a dose-dependent manner.
  • Exercise reduces risk of breast cancer recurrence and mortality among women.
  • Consumption of dairy products - especially high fat products - linked to lower risk of developing diabetes and high blood pressure.
  • Spices dampen pro-inflammatory response to a high-saturated fat, high-carbohydrate meal.

14 - May 15 2020

  • A human monoclonal antibody shows promise against COVID-19.
  • Majority of COVID-19 patients found to be vitamin D deficient.
  • Gut bacteria use flavonoids to prime the body's immune response and protect against influenza.
  • Assessment of cardiorespiratory fitness using submaximal exercise testing predicts 5-year mortality risk beyond conventional risk factors.
  • Greater brain connectivity observed in cognitively intact adults over the age of 95 years.
  • Blood glucose control in type 2 diabetes influences COVID-19 related mortality.
  • Delayed clearance of SARS-CoV-2 in males likely due to high ACE2 expression in testes, which serve as viral reservoirs.
  • Current options for addressing cardiovascular complications of COVID-19.
  • Vitamin D can suppress cytokine storms in COVID-19 patients, reducing mortality.
  • Herpes simplex virus I promotes formation of amyloid-beta plaques in brain cells.

13 - May 1 2020

  • Poor vitamin D status was prevalent among patients with acute respiratory distress syndrome.
  • Betacoronaviruses as a group, including SARS-CoV-2, produce antibodies that can either confer immunity or cross-react with other viral family members.
  • People with COVID-19 are at higher risk of complications associated with thrombotic events.
  • Omega-3 fatty acids added to intravenous feedings decrease infection risk and shorten hospital stays.
  • Omega-3 fatty acid supplementation improves behavior in children aged 8 to 16 years.
  • Omega-3 fatty acid supplementation benefits people with depression.
  • A gut-brain axis specific to glucose drives sugar preference, potentially explaining sugar cravings.
  • Zinc reduces the duration and incidence of the common cold.
  • Zinc acetate and zinc gluconate lozenges were equally effective at reducing duration of the common cold. (80-207mg/day)
  • Higher zinc status reduced incidence and duration of pneumonia among nursing home residents.
  • Omega-3 fatty acid supplementation decreased tobacco cravings in smokers.

12 - Apr 17 2020

  • Chloroquine or hydroxychloroquine, when used in combination with metformin, increased risk of death in mice.
  • Exercise might protect against deadly COVID-19 complication (Acute respiratory distress syndrome - ARDS).
  • A 2008 article by Dr. Anthony Fauci identifies pneumonia as the primary cause of death for 1918 pandemic victims, raising alarms about future pandemics.
  • Daytime intermittent fasting for 30 consecutive days was associated with many health improvements.
  • Experimental antiviral drug (EIDD-2801) effective against COVID-19 in mice.
  • Recombinant form of ACE2 reduced SARS-CoV-2 infection in cultured cells.
  • SARS-CoV-2 replicates in the throat, making it more contagious than other coronaviruses.
  • Cardiac injury commonly occurs in patients with COVID-19, increasing the risk of death among patients with preexisting cardiovascular disease.
  • Exercise improved cognitive function in overweight children.
  • Seasonal variation in Nrf2 antioxidant pathway influences winter depression-like behavior in fish.

11 - Apr 3 2020

  • Subgroups of children could be at greater risk of COVID-19, especially those who are younger, have respiratory problems, or are immunocompromised.
  • Some COVID-19 patients report loss of smell and taste, potentially signaling SARS-CoV-2 infiltration of the central nervous system.
  • Treatment with intravenous vitamin C reduced death rates in patients with sepsis and severe acute respiratory failure.
  • Large doses of vitamin C up to 8 grams per day might reduce duration of the common cold.
  • Vitamin C might reduce the duration of mechanical ventilation in critically ill patients.
  • Vitamin C reduces C-reactive protein among some groups of people.
  • Vitamin C increased the bioavailability of the catechins present in green tea.
  • Evidence suggests vitamin C substantially reduces bronchoconstriction caused by exercise.
  • Large doses of vitamin C might mitigate the body's stress response, thereby improving immunity. (200mg/daily for mice)
  • Vitamin C deficiency impairs fatty acid oxidation ("fat burning") during exercise.

10 - Mar 20 2020

  • An open-label pilot trial found that the antimalarial drug hydroxychloroquine may be useful in the treatment of COVID-19.
  • Phase 1 clinical trial of investigational vaccine for COVID-19 begins.
  • Potential targets for immune responses to novel coronavirus have been identified, a crucial step in vaccine development.
  • US military scientists working to develop a therapeutic strategy against SARS-CoV-2
  • More than 10 percent of people with COVID-19 are infected by someone who has the SARS-CoV-2 virus but is asymptomatic.
  • Case report suggests that SARS-CoV-2 is not transmitted from pregnant mothers to their infants.
  • Brain aging emerges in a person's late 40's but dietary ketosis increases overall brain activity and stabilizes functional networks.
  • Diet-induced thermogenesis is higher after breakfast than after dinner.
  • Mental stress and lifestyle can predict lifespan.
  • Exercise benefits men about to undergo prostate cancer treatment.
  • Chronic sleep deprivation impairs immune function.
  • Healthy lifestyle reduces risk of disease and death.
  • Athletes who engage in indoor sports may be at risk for vitamin D deficiency.

9 - Mar 6 2020

  • Eating earlier in the day promotes lipid oxidation (fat burning).
  • Drinking a high flavanol cocoa beverage reduced symptoms of peripheral arterial disease.
  • Adherence to the Mediterranean diet for one year promotes gut bacteria linked to healthy aging in older adults.
  • Extra virgin olive oil maintains its health-promoting properties when used for cooking.
  • Dietary olive oil may improve healthspan and delay aging by switching on the activity of sirtuins.
  • Obesity promotes diversity and virulence of influenza virus.
  • Antidepressant discontinuation triggers agitation, headaches, and flu-like symptoms.
  • The negative effects of obesity mimic the aging process.
  • Sugar-sweetened beverages linked to lipid imbalance, which increases cardiovascular disease risk.
  • Excess visceral fat promotes inflammation and drives cognitive decline.
  • Global air pollution shortens people's lives on a scale greater than warfare, other forms of violence, infection, and more.
  • Consuming diet drinks along with carbohydrates may have negative effects on the brain and metabolic health.
  • Brain tissue levels of iron during adolescence influence cognitive abilities.

8 - Feb 21 2020

  • When healthy, lean individuals ate a Western-style diet for one week, their hippocampal-dependent learning and memory and appetite control declined. (High refined carbs, added fats, sodium, low grains/veg/fruit).
  • Low maternal vitamin D levels in early to mid-pregnancy were associated with an increased risk for offsprint ADHD.
  • Sauna use reduces pneumonia risk in healthy, middle-aged men.
  • Weight loss and health improvements with Mediterranean, intermittent fasting, and Paleo diets.
  • Six months of aerobic exercise improved brain glucose metabolism, improved executive function, & increased cardiorespiratory fitness in older adults.
  • Many dietary supplements may be contaminated with heavy metals or microbes or may contain synthetic drugs or ingredients not listed on their labeling.
  • Japanese sake yeast supplementation improves sleep quality in a double-blind randomized controlled clinical trial.
  • Breast milk components affect infant growth and help prevent obesity in early childhood.
  • Children of women exposed to parabens during pregnancy are at greater risk of being obese.
  • Physical inactivity and sedentary behavior may be early risk factors for depression in adolescence.

7 - Feb 7 2020

  • Sulforaphane from broccoli sprout extract improves fasting glucose and HbA1c in obese patients with poorly controlled type 2 diabetes.
  • High and low exercise intensities elicit different effects on brain function.
  • Yoga increases brain levels of the neurotransmiter GABA to reduce symptoms of depression.
  • Abdominal obesity is associated with fatal heart attacks and strokes independent of other risk factors.
  • Stress caused hair to turn prematurely gray in mice by activating noradrenaline.
  • Intranasal oxytocin spray decreased repetitive behaviors and improved social interaction in men with autism.
  • Alcohol and cigarettes may accelerate brain aging.
  • Exposure to influenza viruses during childhood may provide partial lifelong protection against distantly related influenza.
  • Sleep duration may influence children's mental health.
  • Lithium may halt the progression of Alzheimer's disease.
  • Increasing stem cell populations improves learning and memory in old mice.

6 - Jan 24 2020

  • Eating a low-fat diet may reduce testosterone levels in men.
  • Preliminary findings suggest that women taking oral contraceptives have a smaller hypothalamus.
  • Fish oil supplementation provides protection against fine particulate air pollution.
  • Brake dust air pollution may have the same harmful effects on immune cells as diesel exhaust.
  • One night of sleep deprivation in healthy young men caused increased blood levels of tau, a protein that forms tangles in the brain.
  • Disrupted glucose metabolism may be a major contributing factor to Alzheimer's disease.
  • Fasting reduces the numbers of circulating monocytes in healthy humans and mice without compromising immune function.
  • Drinking tea at least three times a week is linked with a longer and healthier life.
  • Students who smoked were two to three times more likely to develop depression than students who never smoked.
  • Early life bacterial exposures influence immune health.
  • Alterations in gut microbial fermentation module the efficacy of exercise for diabetes prevention and management.
  • Decreasing the insulin signaling pathway and the TOR pathway increased lifespan of worms by 500 percent.
  • Meta-analysis finds that quercetin significantly lowers blood pressure.

5 - Jan 10 2020

  • Higher cardiorespiratory fitness associated with increases in gray matter volume.
  • More abdominal fat drives loss of fluid intelligence whereas more muscle mass protects against loss.
  • Exercise mitigates muscle mass losses during severe energy deficit by inhibiting the induction of autophagy.
  • Boys whose mothers were overweight or obese during pregnancy scored 5 or more points lower on IQ tests at age 7.
  • Omega-3 fatty acid supplementation increases blood levels of anti-inflammatory molecules for up to 24 hours after ingestion.
  • Low levels of omega-3 fatty acids are associated with early-onset coronary atherosclerosis.
  • Biological "aortic age" of the heart reduced by approximately four years in first-time marathon runners.
  • Cognitive-behavioural therapy reduces symptoms of social anxiety disorder and improves biomarkers of aging.
  • Higher physical activity halves risk of depression in a large study of more than 395,000 adults.
  • A vaccine developed to prevent tuberculosis, now also used to treat bladder cancer, reduced the incidence of Alzheimer's disease four-fold.
  • Hyperbaric oxygen therapy demonstrates efficacy in treating symptoms of Alzheimer's disease.
  • Stressed mitochondria leak DNA fragments that induce inflammation.

2019

4 - Dec 27 2019

  • Yoga increases the volume of a brain region involved in learning and memory and changes several brain regions involved in emotional regulation.
  • More than half of people suffer withdrawal effects when trying to come off antidepressants.
  • Effects of hyperthermic baths on depression, sleep, and heart rate variability in patients with depressive disorder.
  • Increasing gamma rhythm activity in the brain can affect the pathology and symptoms of Alzheimer's disease.
  • Depression and suicide linked to air pollution.
  • Ketamine disrupts memories to help heavy drinkers cut back.
  • Early epigenetic changes in mice regulate voluntary exercise behaviour.
  • Post-workout ice baths may hinder muscle protein synthesis.
  • High glycemix index diets may trigger insomnia.
  • Fish oil supplementation may improve night vision.
  • FDA approves use of drug (Vascepa) to reduce risk of cardiovascular events in certain adult patient groups. (reduces triglycerides)
  • Immunization against flagellin provides protection against chronic inflammatory disease in mice.
  • Sustained weight loss in women over 50 reduces breast cancer risk.

3 - Dec 3 2019

  • IQs of children whose mothers consumed fish during pregnancy nearly 5 to 10 points higher than those of children whose mothers did not eat fish.
  • Maternal dietary intake of omega-3 fatty acids has beneficial effects on infant brain development.
  • A new, more accurate test finds that human urine samples contain BPA levels up to 44 times higher than measurements by the FDA.
  • A group of proteins identified in human plasma predicts both chronological and biological age.
  • A compound that blocks a key inflammatory pathway in the brain reverses cognitive decline in mice.
  • Time-restricted eating may help reduce weight and prevent diabetes and heart disease in people with metabolic syndrome.
  • Supplementation with Akkermansia muciniphila improves metabolic parameters in overweight and obese people.
  • Obese adolescents have decreased white matter in a brain region that connects the right and left hemispheres of the brain (compared to healthy teens).
  • Aerobic exercise combined with frequent sauna use has a synergistic effect on lowering mortality risks.
  • After bone marrow transplant, man's semen contains only donor's DNA.
  • Prostate cancer was completely eliminated in 80 percent of men treated with MRI-guided ultrasound (transurethral ultrasound ablation).

2 - Nov 29 2019

  • Inflammation may play a causal role in diminishing certain cognitive functions.
  • Increased physical activity may significantly reduce the risk of depression, even among people who are genetically predisposed to depression.
  • High-intensity interval training improves memory in older adults.
  • Supercentenarians (110yo+) have high levels of cytotoxic CD4 T cells, which can kill cancer cells.
  • Mild hearing loss - when hearing is still considered normal - is linked to cognitive decline.
  • Gut bacteria may alter the aging process of the human brain.
  • Fecal samples from people with colorectal cancer transplanted into mice caused precancerous lesions.
  • Diets high in ultra-processed food linked to poor cardiovascular health.
  • Sugar binges increase risk of inflammatory bowel disease.
  • Mice fed a high-fat, low-carbohydrate diet were better able to combat the flu virus and had better survival rates than mice fed a normal diet.
  • Screen time exposure begins in infancy and increases with age.

1 - Nov 15 2019

  • A single night of sleep deprivation increased anxiety levels by 30 percent in healthy young adults.
  • Waves of Fluid Bathe the Sleeping Brain, Perhaps to Clear Waste (glymphatic system)
  • Running associated with lower all-cause, cardiovascular, and cancer mortality.
  • Time-restricted eating may be linked to greater motivation to engage in voluntary exercise.
  • Study demonstrates that exercising before eating breakfast burns more fat, improves insulin sensitivity, & increases glucose uptake into muscle.
  • New data suggest the human heart adapted to ensure regular bouts of sustained moderate-intensity endurance exercise and is partly dependent upon it.
  • Metformin supplementation prevented gains in lean muscle mass in healthy people 65 years and older who engaged in resistance training.
  • When mothers were more interactive with their infant during a play activity, epigenetic changes occurred in the infant's DNA.
  • Human longevity was associated with decreased levels of genes involved in neural overactivity.
  • Infants given formula containing milk fat globule membranes (found in human breast milk) scored better on tests of cognitive, language & motor skills.
  • Eating an avocado a day lowered small, dense LDL particles and lowered oxidized LDL, both of which are associated with heart disease.
  • A new drug (Trikafta) may extend the lifespan of people with cystic fibrosis.

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