Scripts to reproduce the experiments performed for the TrajGWAS manuscript:
Ko S, German CA, Jensen A, Shen J, Wang A, Mehrotra DV, Sun YV, Sinsheimer JS, Zhou H, Zhou JJ. GWAS of longitudinal trajectories at biobank scale. The American Journal of Human Genetics. In press. doi:10.1016/j.ajhg.2022.01.018.
Scripts for reproducing simulation studies. Experiments are conducted with an older version of TrajGWAS, named vGWAS. This version of package is kept on the branch gwas_dev of the package repository. You can load this version following the instruction inside the directory.
Scripts for UK Biobank data analyses. It can run with TrajGWAS v0.1.2. Its optimization interface has changed to MathOptInterface since v0.4, and KNITRO.KnitroSolver no longer works. Use
solver = KNITRO.Optimizer()
solver_config = Dict("outlev" => 3)as keyword arguments for the trajgwas() function instead to run with newer version of TrajGWAS and KNITRO.