kauralasoo / Regenie-Nextflow-pipeline

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Regenie-Nextflow-pipeline

Regenie example workflow

  • Analysing multiple phenotypes at the same time
  • Using quantitative traits
  • Outputting the results as one zip file for each phenotype
  • Producing Manhattan plot for each phenotype

Mandatory input parameters in nextflow.config file

  • params.step1_pgen : pgen files.{pgen,psam,pvar} for step 1
  • params.step2_pgen : pgen files.{pgen,psam,pvar} for step 2
  • params.phenotype_file : phenotypes file , for more details about the format, review regiene documentations
  • params.phenotype_list : comma separated list of phenotypes to include in the analysis
  • params.covariate_file : covariates file , for more details about the format, review regiene documentations
  • params.covariate_list : comma separated list of covariates to include in the analysis
  • params.outdir : directory of the output
  • params.prefix : name of the root output file

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