jwonged / Bioinformatics

Implementation of various bioinformatics algorithms

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Bioinformatics

Implementation of various algorithms from bioinformatics

Sequence Alignment

Genetic sequences can be represented as vectors of chars (e.g. AGCT for DNA). The alignment of sequences reveal sites with the same ancestry.

GlobalSequenceAlignment.java

Implements a dynamic programming algorithm for global sequence alignment based on a scoring matrix.

Phylogeny

Phylogeny is about taking multiple alignments of genome sequences and inferring an evolutionary relationship between them. These allow the creation of evolutionary trees that tell us about the common ancestors between species, where they diverged and what the relationships between them are.

The Neighbour Joining algorithm is provided in:

NeighbourJoinMain.java

It always produces a tree if the input matrix is additive. Otherwise, it provides a heuristic for such a tree.

Exact Pattern Matching

Suffix Trie

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Implementation of various bioinformatics algorithms


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