A lightweight shiny application to visualize gene models and supporting reads.
shiny::runApp() when in the root directory should launch the current
version of the app.
The goal is to produce a shiny application that allows the user to specify a gene symbol and BAM file(s), and be rewarded with a visualization displaying the gene model (exons organized into transcripts) and supporting reads. The application should use the release version of Bioconductor.
For gene models, the server might consult org.Hs.eg.db to map from gene symbol to Entrez gene id, then extract the gene model from the appropriate TxDb.Hsapiens.* (these steps might be combined using Homo.sapiens).
For coverage, Rsamtools might be handy, using the range() of the gene model.
For display, the server might use Gviz to visualize the gene model, and to add coverage track(s).
The resulting application should be easy enough to understand. An only moderately experienced Bioconductor user should feel like they themselves could build the app from scratch.