hugo1005 / A-Model-Based-Approach-To-Assess-Epidemic-Risk

Dolan, H., Rastelli, R. A Model-Based Approach to Assess Epidemic Risk. Stat Biosci (2021). https://doi.org/10.1007/s12561-021-09329-z

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A-Model-Based-Approach-To-Assess-Epidemic-Risk

Hugo Dolan, Riccardo Rastelli

Abstract

We study how international flights can facilitate the spread of an epidemic to a worldwide scale. We combine an infrastructure network of flight connections with a population density dataset to derive the mobility network, and then define an epidemic framework to model the spread of disease. Our approach combines a compartmental SEIRS model with a graph diffusion model to capture the clusteredness of the distribution of the population. The resulting model is characterised by the dynamics of a metapopulation SEIRS, with amplification or reduction of the infection rate which is determined by the mobility of individuals. Then, we use simulations to characterise and study a variety of realistic scenarios that resemble the recent spread of COVID-19. Crucially, we define a formal framework that can be used to design epidemic mitigation strategies: we propose an optimisation approach based on genetic algorithms that can be used to identify an optimal airport closure strategy, and that can be employed to aid decision making for the mitigation of the epidemic, in a timely manner.

About this repository

This repository contains copies of the original datasets used in this project in the "/datasets" folder. It also contains 2 python files, which contain the entire simulation environment (environment.py) and also a script for percolating networks by various factors (percolation.py). Additionally there are 3 notebooks which contain examples of how this code is used in practice as well as the majority of the data processing pipepline, many experimental results and our genetic algorithm procedure. This repository is accompanied by the paper which is found in pdf form and also can be found at https://arxiv.org/abs/2009.12964

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Dolan, H., Rastelli, R. A Model-Based Approach to Assess Epidemic Risk. Stat Biosci (2021). https://doi.org/10.1007/s12561-021-09329-z


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