hincz-lab / microrna

Theoretical calculations and plotting routines related to "Bioenergetic costs and the evolution of noise regulation by microRNAs"

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Numerical calculations and plotting routines related to the article: "Bioenergetic costs and the evolution of noise regulation by microRNAs" (https://doi.org/10.1101/2023.03.28.534633) by Efe Ilker (https://github.com/eilker) and Michael Hinczewski

Description of files:

  • Noise filter calculations for Figs 2 and 3.nb: Mathematica notebook containing calculations relating to the noise filter analysis of the microRNA network.
  • fig2, fig3: Directories containing the data generated by the above notebook.
  • Plotting routines for Figs 2 and 3.ipynb: Jupyter notebook to generate Figures 2 and 3 using Python matplotlib.
  • KD analysis/MiRNA KD analysis.nb: Mathematica notebook for the dissociation constant analysis (Fig. S2)
  • KD analysis/miR_Family_Info.txt: Seed sequences from TargetScanHuman database v.7.1 (https://www.targetscan.org/vert_71/)
  • figS1: directory with data for Fig. S1

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Theoretical calculations and plotting routines related to "Bioenergetic costs and the evolution of noise regulation by microRNAs"


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Language:Mathematica 75.0%Language:Jupyter Notebook 25.0%