eolivaresb / Globus-pallidus-network

Computational model for the globus-pallidus using phase model and experimental phase resetting curves

Globus-pallidus-network

Code for simulations, analysis and plots on the article:

• "Mutual inhibition in a model of the indirect pathway globus pallidus network slows and deregularizes background firing, but sharpens and synchronizes responses to striatal input" *

Erick O. Olivares, Matthew H. Higgs, and Charles J. Wilson

If you have any question please contact Erick Olivares [e-mail] [e-mail]

Large data files has been removed, they can be retrieved from code or sent upon request.

List of figures and respective code location:

Figure 1:

Simulating GPe neurons using a phase model.

Location "./simulating_oscillators/"

Figure 2:

Characterizing and reconstructing phase resetting curves of iGPe neurons.

Location "./simulation_files/PRCs/"

Figure 3:

Connectivity, rate and regularity of the small-world and random networks.

Location "./intrinsic_dynamic/"

Figure 4:

Simulated GPe neurons’ responses to an inhibitory synaptic barrage.

Location "./simulating_oscillators/"

Figure 5:

Pairwise spike train correlations.

Location "./intrinsic_dynamic/"

Figure 6:

Collective and example individual responses to a brief inhibitory input.

Location "./Shared_input_stimulation/PSTH_analysis/"

Figure 7:

Determinants of the width of the PSTH primary response.

Location "./Shared_input_stimulation/PSTH_analysis/"

Figure 8:

The secondary response in the connected network.

Location "./Shared_input_stimulation/PSTH_analysis/"

Figure 9:

The timing of disinhibition and recovery from inhibition determines the responses of individual neurons in the connected network.

Location "./Shared_input_stimulation/PSTH_analysis/"