Based on an example by probable-basilisk - link to example
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Download this and unzip the folder inside noita's mods folder
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Open
start_twitch.bat
and it will open a browser window with the control panel, head to the Twitch tab and write your twitch channel name, scroll down and click apply -
Go to your mods menu and enable Twitch-helper
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New game and scroll down for the twitch integration gamemode
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[Optional] make a shortcut of start_twitch.bat and put it on your desktop for ease of access
More instructions on how to use it soon