chhylp123 / hifiasm

Hifiasm: a haplotype-resolved assembler for accurate Hifi reads

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Why more contigs always present in haplotype 1 than haplotype 2?

Chenglin20170390 opened this issue · comments

Hi, I found that the contig number of haplotype 1 from hifiasm are always large contig number of haplotype 2.
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What causes this? Is there any explanation in the article (https://www.nature.com/articles/s41587-022-01261-x)?

Sorry for the late reply. I feel like in most cases, hifiasm may put unphased contigs to hap1, making hap1 has more small contigs.

Thanks for your explanations!