celinesoeiro / TCM-Model-old

Model of the Thalamo-Cortical Microcircuit - Please, refer to the new repository https://github.com/celinesoeiro/TCM-model

[Under construction]

TCM-Model

Goal

The purpose of this work is to study the Deep Brain Stimulation (DBS) in the Thalamo-Cortical Microcircuit (TCM).

This will accomplished with the creation of a completely new model using Python.

This model is based on Farokhniaee and Lowery, 2021

Steps

• Step 1 - Create a neuron model using Izhikevich model Izhikevich, 2003
• Step 2 - Create a synaptic model using Tsodyks and Markram (Tsodyks and Markram, 1997)
• Step 3 - Create the thalamo-cortical model using Farokhniaee and Lowery as reference (Farokhniaee and Lowery, 2021)
• Step 4 - Add DBS stimulation

General files

• tcm_params
• model_plots
• model_functions

Step 1

Files

• izhikevich_neuron
• izhikevih_neuron/izhikevich_neuron_simulations
• izhikevih_neuron/izhikevich_neuron_simulations

How to run

Step 2

Files

• TM_syn_FS
• TM_syn_IB
• TM_syn_LTS
• TM_syn_RS
• TM_syn_TC
• TM_syn_TR
• tm_synapse_all

How to run

Step 3

Files

• step-1-cortical-D
• step-2-cortical-DS
• step-3-cortical
• step-4-thalamus-unreal
• step-4-thalamus

How to run

Step 4

Files

• TR_nucleus_DBS
• TC_nucleus_DBS
• CI_nucleus_DBS
• D_nucleus_DBS
• M_nucleus_DBS
• S_nucleus_DBS
• DBS
• dbs_modes

How to run