brentp / mosdepth

fast BAM/CRAM depth calculation for WGS, exome, or targeted sequencing

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question: `--by` and quantized output

matthdsm opened this issue · comments

Hi Brent

Is the quantized output supposed to be filtered by the regions given in --by ? I'm trying to create "callable" loci within a set ROI for exome analysis.

Thanks
M

Hi Matthias, no, it still outputs the full genome. But it should be simple to do a bedtools intersect with target regions afterward.

guessed something like that. Thanks for the reply!

Matthias