VCF Annotation Tools is a python package that includes several tools to annotate VCF files with data from other tools.
vcf-readcount-annotator
A tool that will add the data from bam-readcount files to the VCF sample column.
vcf-expression-annotator
A tool that will add the data from several expression tools’ output files to the VCF INFO column. Supported tools are StringTie, Kallisto, and Cufflinks. There also is a custom option to annotate with data from any tab-delimited file.
vcf-info-annotator
A tool that will add data from a tab-delimited file to any user-specified field in the VCF INFO column.
vcf-genotype-annotator
A tool to add a new sample to an existing VCF file.
vep-annotation-reporter
A tool to create a tab-delimited (TSV) file of variants in a VCF and their VEP annotations.
transform-split-values
A tool that extracts and manipulates values from existing sample fields and outputs the results to a TSV file.
Please see vatools.org for the full documentation.
pip install vatools