Runs independently of the protein primary sequence.
Subsecond performance
Takes as input PDB files for the 2 proteins.
Store pdb data files in ./files
- git clone https://github.com/ayushchopra96/topologize.git
- cd topologize
- sh generate_executable.sh
- ./a.out ./path/to/pdb1 ./path/to/pdb2
Outputs scaled metric value for the structural topology similarity.
Result Analysis:-
1. output result > 0.72 :- High level of structural similarity
2. output result < 0.45 :- No structural similarity
3. 0.72 > output > 0.45 :- Partial Structural Similarity